Selected Publications

Beggs HE, Schahin-Reed D, Zang K, Goebbels S, Nave KA, Gorski J, Jones KR, Sretavan D, Reichardt LF: FAK deficiency in Cells Contributing to the Basement Membrane Results in Cortical Abnormalities Resembling Congenital Muscular Dystrophies. Neuron, 2003: 40(3) 501-514.

Liu G*, Beggs HE*, Park H.-T, Tang H, Xiong W.-C, Reichardt LF, Wu J, Rao Y: Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction. Nature Neuroscience, 2004: 7(11) 1222-1232.

(* co-first author)

Rico B, Beggs HE, Schahin-Reed D, Kimes N, Schmidt A, Reichardt LF: Control of Axonal Branching and Synapse Formation by Focal Adhesion Kinase. Nature Neuroscience 2004: 7(10): 1059-1069.

Tilghman, R.W., Slack-Davis, J.K., Sergina, N., Martin, K.H., Iwanicki, M., Hershey, D., Beggs, H.E, Reichardt, L. and Parsons, J.T. (2005) Focal Adhesion Kinase is required for the spatial organization of the leading edge in migrating cells. J. Cell Science. 118: 2613-23.

Essayem S, Kovacic-Milivojevic B, Baumbusch C, McDonagh S, Dolganov G, Howerton K, Larocque N, Ramiriz A, Ramos DM, Fisher SJ, Jorcano JL, Beggs H, Reichardt, LF, Ilic, D (2006) Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK. Oncogene. 25:1081-9

Braren R, Hu H, Beggs HE, Reichardt LF, Wang R: Cre-Mediated Deletion of fak in the Circulatory System Disrupts Vascular Remodeling. (2006) J. Cell Biology 172: 151-162.

DiMichele LA, Doherty J, Rojas M, Beggs HE, Reichardt LF, Mack CP, Taylor JM (2006) FAK is required for pathological hypertrophic cardiac remodeling but not for maintaining physiological heart function. (Accepted, Circulation Research)

Sundberg LJ, Thompson R, Beggs HE, Reichardt LF, Mack CP, Taylor JP. (2006) Inactivation of Focal Adhesion Kinase promotes smooth muscle cell differentiation. (Accepted, JBC).

Shober, M., Raghavan, S., Nikolova, M., Polak, L., Pasolli, A., Beggs, H., Reichardt L.F. and Fuchs E. (2006) Defining roles for focal adhesion kinase in actin dynamics and focal adhesion turnover. (Submitted)

Hakim, ZS, DiMichele LA, Doherty JT, Homeister JW, Beggs HE, Reichardt LF, Schwartz RJ, Mack CP, Taylor JP (2006) Embryonic myocyte-restricted deletion of focal adhesion kinase leads to septal defects and perinatal lethality. (Submitted).