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Professional
/ Research Summary
Signaling
mechanisms in corneal inflammation and angiogenesis
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| Ocular
surface inflammation represents a complex multistep process that involves
expression of cytokines and adhesion molecules, recruitment of inflammatory
cells, expression of growth factors, and extracellular matrix remodeling.
Accumulating evidence suggests a major co-dependence and integration
of the processes of inflammation and angiogenesis. My research program
investigates molecular signaling pathways in ocular surface inflammation
and pathologic angiogenesis. The goals of this research are to provide
insights into the signaling events involved in the initiation, maintenance,
and resolution of an ocular inflammatory response, and identify novel
targets for therapeutic intervention. |
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